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Lgr5em1Smoc
Endonuclease-mediated Allele Detail
Summary
Symbol: Lgr5em1Smoc
Name: leucine rich repeat containing G protein coupled receptor 5; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
MGI ID: MGI:7766310
Synonyms: Lgr5em1(flox)Smoc
Gene: Lgr5  Location: Chr10:115286219-115423685 bp, - strand  Genetic Position: Chr10, 63.51 cM
Alliance: Lgr5em1Smoc page
Mutation
origin
Strain of Origin:  C57BL/6JSmoc
Mutation
description
Allele Type:    Endonuclease-mediated (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation detailsThis allele contains loxP sites flanking exon 16 of the gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of the gene. (J:238766)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Lgr5 Mutation:  58 strains or lines available
References
Original:  J:238766 Shanghai Model Organisms Center, Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China. MGI Direct Data Submission. 2017;
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/30/2025
MGI 6.24
The Jackson Laboratory