Dio3^tm2Stg
Targeted Allele Detail

Summary

• Symbol: Dio3^tm2Stg
• Name: deiodinase, iodothyronine type III; targeted mutation 2, Donald St Germain
• MGI ID: MGI:7736212
• Gene: Dio3 Location: Chr12:110245664-110247531 bp, + strand Genetic Position: Chr12, 60.56 cM, cytoband F1
• Alliance: Dio3^tm2Stg page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:218428
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• The targeting construct replaced the coding sequence with a neomycin selection cassette. (J:218428)

Expression

In Mice Carrying this Mutation:

9 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Dio3 Mutation: 7 strains or lines available

References

• Original: J:218428 Martinez ME, et al., Genomic imprinting variations in the mouse type 3 deiodinase gene between tissues and brain regions. Mol Endocrinol. 2014 Nov;28(11):1875-86
• All: 1 reference(s)