Rbp3^tm1.1Jmni
Targeted Allele Detail

Summary

• Symbol: Rbp3^tm1.1Jmni
• Name: retinol binding protein 3, interstitial; targeted mutation 1.1, John M Nickerson
• MGI ID: MGI:7718616
• Gene: Rbp3 Location: Chr14:33675960-33686173 bp, + strand Genetic Position: Chr14, 20.8 cM
• Alliance: Rbp3^tm1.1Jmni page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:353299
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Targeted (Not Applicable)
• Mutation: Insertion
• Mutation details: The targeting vector inserted a 3' loxP site at 3117 bp downstream from the transcription start site in the first intron. Flp-recombinase removed an FRT-flanked selection cassette leaving a single 3' loxP in the Rbp3 gene. (J:353299)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Rbp3 Mutation: 90 strains or lines available

References

• Original: J:353299 Getz TE, et al., Conditional Knockouts of Interphotoreceptor Retinoid Binding Protein Suggest Two Independent Mechanisms for Retinal Degeneration and Myopia. Invest Ophthalmol Vis Sci. 2024 Jun 3;65(6):32
• All: 1 reference(s)