Lrrc59^em1(IMPC)J
Endonuclease-mediated Allele Detail

Summary

• Symbol: Lrrc59^em1(IMPC)J
• Name: leucine rich repeat containing 59; endonuclease-mediated mutation 1, Jackson
• MGI ID: MGI:7714743
• Gene: Lrrc59 Location: Chr11:94520603-94536049 bp, + strand Genetic Position: Chr11, 58.9 cM
• Alliance: Lrrc59^em1(IMPC)J page
• IMPC: Lrrc59 gene page

Mutation origin

• Strain of Origin: C57BL/6NJ
• Project Collection: IMPC

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: This allele was generated at The Jackson Laboratory by electroporating Cas9 protein and 2 guide sequences: GCTGTTTTACAAGCTTGTCT and CTGCAGGCTGATTAAGGACA. This resulted in a 4,299 bp deletion of Chr11:94,634,348-94,638,646 (GRCm38/mm10) that removes exons ENSMUSE00001286541 through ENSMUSE00000110773. (J:188991)
• Inheritance: Not Specified

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available
• Carrying any Lrrc59 Mutation: 20 strains or lines available

References

• Original: J:188991 The Jackson Laboratory, Alleles produced for the KOMP project by The Jackson Laboratory. MGI Direct Data Submission. 2012
• All: 1 reference(s)