Pten^tm1.1Ayr
Targeted Allele Detail

Summary

• Symbol: Pten^tm1.1Ayr
• Name: phosphatase and tensin homolog; targeted mutation 1.1, Alexander Y Rudensky
• MGI ID: MGI:7714642
• Gene: Pten Location: Chr19:32734977-32803560 bp, + strand Genetic Position: Chr19, 28.14 cM
• Alliance: Pten^tm1.1Ayr page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:101977
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: (129S6/SvEvTac x C57BL/6J)F1

Mutation description

• Allele Type: Targeted (Reporter)
• Mutation: Insertion
• Mutation details: A furin cleavage linker-T2A-EYFP-FRT-PGK-Neomycin/Kanamycin-bGH pA-FRT cassette was inserted immediately upstream of the stop codon in exon 9 (the last exon) of the mouse Pten gene via homologous recombination. The FRT-flanked drug selection cassette was excised by crossing with R26 FLP mice. (J:101977)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Pten Mutation: 87 strains or lines available

References

• Original: J:101977 The Jackson Laboratory, Information obtained from The Jackson Laboratory, Bar Harbor, ME. Unpublished. 2005-2017
• All: 1 reference(s)