Fmn2^em1(IMPC)Mbp
Endonuclease-mediated Allele Detail

Summary

• Symbol: Fmn2^em1(IMPC)Mbp
• Name: formin 2; endonuclease-mediated mutation 1, Mouse Biology Program, UC Davis
• MGI ID: MGI:7711999
• Gene: Fmn2 Location: Chr1:174329391-174650295 bp, + strand Genetic Position: Chr1, 81.04 cM
• Alliance: Fmn2^em1(IMPC)Mbp page
• IMPC: Fmn2 gene page

Mutation origin

• Strain of Origin: C57BL/6NCrl
• Project Collection: IMPC

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: This allele was generated at University of California, Davis using Cas9 and guides with spacer sequences ATAGAGGCCATTCTTTTTTG and GCCACAGCATCTGCCCTTAC that targeted exon(s) ENSMUSE00000972573.2. This resulted in deletion(s) of 4 bp (location: Chr1:174365492-174365495; GRCm39), 912 bp (location: Chr1:174364390-174365301; GRCm39). This description was generated automatically. Additional molecular information including FASTA sequence support for this allele can be found here: (IMPC Gene page) and viewed in a genome context here: (IMPC Genome Browser). (J:384794)

• Inheritance: Not Specified

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Fmn2 Mutation: 77 strains or lines available

References

• Original: J:265051 MGI and IMPC, MGI Load of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC). Database Release. 2018-2023
• All: 2 reference(s)