Del(5Rr514-Rr117742)1Josv
Endonuclease-mediated Allele Detail

Summary

• Symbol: Del(5Rr514-Rr117742)1Josv
• Name: deletion, Chr 5, John Svaren 1
• MGI ID: MGI:7711955
• Gene: Del(5Rr514-Rr117742)1Josv Location: unknown Genetic Position: Chr5, Syntenic

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Modified regulatory region)
• Mutation: Intergenic deletion
• Del(5Rr514-Rr117742)1Josv involves 2 genes/genome features (Rr514, Rr117742) View all
• Mutation details: Two Ssh enhancers, located upstream, were targeted using two sgRNAs with CRISPR/Cas9 technology, resulting in an ~11 kb deletion. This allele was created in conjunction with the Rr515^em1Josv allele. (J:346234)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Del(5Rr514-Rr117742)1Josv Mutation: 0 strains or lines available

References

• Original: J:346234 Ramesh R, et al., JUN Regulation of Injury-Induced Enhancers in Schwann Cells. J Neurosci. 2022 Aug 24;42(34):6506-6517
• All: 1 reference(s)