Bag1^em1Mpup
Endonuclease-mediated Allele Detail

Summary

• Symbol: Bag1^em1Mpup
• Name: BCL2-associated athanogene 1; endonuclease-mediated mutation 1, Tohoku Medical and Pharmaceutical University, Faculty of Phamaceutical Sciences
• MGI ID: MGI:7705901
• Gene: Bag1 Location: Chr4:40936398-40948294 bp, - strand Genetic Position: Chr4, 20.67 cM, cytoband B1
• Alliance: Bag1^em1Mpup page

Mutation origin

• Strain of Origin: B6D2F1

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR-targeting removed exon 5. (J:352269)
• Inheritance: Not Specified

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Bag1 Mutation: 19 strains or lines available

References

• Original: J:352269 Inose-Maruyama A, et al., Bag1 protein loss sensitizes mouse embryonic fibroblasts to glutathione depletion. Cell Stress Chaperones. 2024;29(3):497-509
• All: 1 reference(s)