Id1^tm1.1Jrk
Targeted Allele Detail

Summary

• Symbol: Id1^tm1.1Jrk
• Name: inhibitor of DNA binding 1, HLH protein; targeted mutation 1.1, Jonathan R Keller
• MGI ID: MGI:7705178
• Gene: Id1 Location: Chr2:152578171-152579330 bp, + strand Genetic Position: Chr2, 75.41 cM
• Alliance: Id1^tm1.1Jrk page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:271558
• Parent Cell Line: Bruce 4 (ES Cell)
• Strain of Origin: B6.Cg-Thy1^a

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Mutation details: A loxP site was inserted upstream of exon 1 and an FRT-flanked neomycin selection cassette and a second loxP site were inserted downstream of exon 2. The neo cassette was removed with Flp recombinase. (J:271558)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Id1 Mutation: 11 strains or lines available

References

• Original: J:271558 Singh SK, et al., Id1 Ablation Protects Hematopoietic Stem Cells from Stress-Induced Exhaustion and Aging. Cell Stem Cell. 2018 Aug 2;23(2):252-265.e8
• All: 1 reference(s)