Ace2^em8(ACE2)Cya
Endonuclease-mediated Allele Detail

Summary

• Symbol: Ace2^em8(ACE2)Cya
• Name: angiotensin converting enzyme 2; endonuclease-mediated mutation 8, Cyagen Biosciences
• MGI ID: MGI:7657429
• Synonyms: Ace2^em1(hACE2)
• Gene: Ace2 Location: ChrX:162922338-162971414 bp, + strand Genetic Position: ChrX, 76.12 cM, cytoband F5
• Alliance: Ace2^em8(ACE2)Cya page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Inserted expressed sequence)
• Mutation: Insertion
• Ace2^em8(ACE2)Cya expresses 1 gene
  Knock-in expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  ACE2 (59272)

  Ace2	(MGI:1917258)

• Mutation details: The region from aa.18 to aa.805 of mouse Ace2 was replaced with the region from aa.18 to aa.805 of human ACE2. The murine signal peptide (aa.1~17) remains. (J:326541)
• Inheritance: Not Specified

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ace2 Mutation: 71 strains or lines available

References

• Original: J:326541 Cyagen Biosciences Inc., Cyagen Biosciences Website. 2022
• All: 1 reference(s)