Ttr^tm1(TTR)Cya
Targeted Allele Detail

Summary

• Symbol: Ttr^tm1(TTR)Cya
• Name: transthyretin; targeted mutation 1, Cyagen Biosciences
• MGI ID: MGI:7657337
• Synonyms: Ttr^tm1(hTTR)Cya
• Gene: Ttr Location: Chr18:20798337-20807378 bp, + strand Genetic Position: Chr18, 11.47 cM
• Alliance: Ttr^tm1(TTR)Cya page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:326541
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6N

Mutation description

• Allele Type: Targeted (Inserted expressed sequence, Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Ttr^tm1(TTR)Cya expresses 1 gene
  Knock-in expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  TTR (7276)

  Ttr	(MGI:98865)

• Mutation details: The sequences from ~7.2kb upstream of exon 1 to exon 4 of the mouse Ttr gene will be replaced with the sequences from ~7.2kb upstream of exon 1 to exon 4 of the human TTR gene. (J:326541)
• Inheritance: Not Specified

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ttr Mutation: 40 strains or lines available

References

• Original: J:326541 Cyagen Biosciences Inc., Cyagen Biosciences Website. 2022
• All: 1 reference(s)