Mapt^tm1(MAPT)Cya
Targeted Allele Detail

Summary

• Symbol: Mapt^tm1(MAPT)Cya
• Name: microtubule-associated protein tau; targeted mutation 1, Cyagen Biosciences
• MGI ID: MGI:7657299
• Synonyms: Mapt^{tm1(hMAPT)Cya}
• Gene: Mapt Location: Chr11:104122216-104222916 bp, + strand Genetic Position: Chr11, 67.79 cM, cytoband E1
• Alliance: Mapt^tm1(MAPT)Cya page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:326541
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Targeted (Inserted expressed sequence, Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mapt^tm1(MAPT)Cya expresses 1 gene
  Knock-in expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  MAPT (4137)

  Mapt	(MGI:97180)

• Mutation details: The sequences from the ATG start codon to ~500bp downstream of the endogenous mouse Mapt gene were replaced with the sequences from the ATG start codon to ~500bp downstream of the human MAPT gene, the humanized regions include 3'UTR. (J:326541)
• Inheritance: Not Specified

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Mapt Mutation: 453 strains or lines available

References

• Original: J:326541 Cyagen Biosciences Inc., Cyagen Biosciences Website. 2022
• All: 1 reference(s)