Lep^em3Cya
Endonuclease-mediated Allele Detail

Summary

• Symbol: Lep^em3Cya
• Name: leptin; endonuclease-mediated mutation 3, Cyagen Biosciences
• MGI ID: MGI:7657292
• Synonyms: Lep^{em1(R105X)Cya}
• Gene: Lep Location: Chr6:29060220-29073875 bp, + strand Genetic Position: Chr6, 12.3 cM
• Alliance: Lep^em3Cya page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Not Specified)
• Mutation: Single point mutation
• Mutation details: A 2-base deletion mutation was introduced in Exon 3 of the Lep gene in C57BL/6JCya mice to obtain the Lep KO mouse model. (J:326541)
• Inheritance: Not Specified

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Lep Mutation: 19 strains or lines available

References

• Original: J:326541 Cyagen Biosciences Inc., Cyagen Biosciences Website. 2022
• All: 1 reference(s)