Kras^tm1Cya
Targeted Allele Detail

Summary

• Symbol: Kras^tm1Cya
• Name: Kirsten rat sarcoma viral oncogene homolog; targeted mutation 1, Cyagen Biosciences
• MGI ID: MGI:7657290
• Synonyms: Kras^{tm1(LSL-G12C)Cya}
• Gene: Kras Location: Chr6:145162425-145195965 bp, - strand Genetic Position: Chr6, 77.37 cM, cytoband G2
• Alliance: Kras^tm1Cya page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:326541
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutations: Insertion, Single point mutation
• Mutation details: The loxP-Ad SA-3*SV40 pA-Neo cassette(PGK-Neo-BGH pA)-Stop-loxP gene cassette was inserted into intron 1 of the mouse Kras gene and a G12C mutation was introduced in exon 2. (J:326541)
• Inheritance: Not Specified

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Kras Mutation: 88 strains or lines available

References

• Original: J:326541 Cyagen Biosciences Inc., Cyagen Biosciences Website. 2022
• All: 1 reference(s)