Il17a^{tm1(IL17A)Cya}
Targeted Allele Detail

Summary

• Symbol: Il17a^{tm1(IL17A)Cya}
• Name: interleukin 17A; targeted mutation 1, Cyagen Biosciences
• MGI ID: MGI:7657281
• Synonyms: Il17a^{tm1(hIL17A)Cya}
• Gene: Il17a Location: Chr1:20801129-20804720 bp, + strand Genetic Position: Chr1, 6.45 cM, cytoband A
• Alliance: Il17a^{tm1(IL17A)Cya} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:326541
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6N

Mutation description

• Allele Type: Targeted (Inserted expressed sequence, Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Il17a^{tm1(IL17A)Cya} expresses 1 gene
  Knock-in expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  IL17A (3605)

  Il17a

  (MGI:107364)

• Mutation details: The mouse Il17a endogenous extracellular domain (aa.26~158) was replaced with the human IL17A extracellular domain (aa.24~155). The murine signal peptide (aa.1~25) was kept. (J:326541)
• Inheritance: Not Specified

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Il17a Mutation: 24 strains or lines available

References

• Original: J:326541 Cyagen Biosciences Inc., Cyagen Biosciences Website. 2022
• All: 1 reference(s)