Ighg1^{em2(IGHG1)Cya}
Endonuclease-mediated Allele Detail

Summary

• Symbol: Ighg1^{em2(IGHG1)Cya}
• Name: immunoglobulin heavy constant gamma 1 (G1m marker); endonuclease-mediated mutation 2, Cyagen Biosciences
• MGI ID: MGI:7657262
• Synonyms: Ighj^em1Cya
• Gene: Ighg1 Location: Chr12:113290161-113294143 bp, - strand Genetic Position: Chr12, 62.1 cM
• Alliance: Ighg1^{em2(IGHG1)Cya} page

Mutation origin

• Strain of Origin: C57BL/6N

Mutation description

• Allele Type: Endonuclease-mediated (Inserted expressed sequence, Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Ighg1^{em2(IGHG1)Cya} expresses 1 gene
  Knock-in expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  IGHG1 (3500)

  Ighg	(MGI:2144967)
  Ighg1	(MGI:96446)
  Ighg2a	(MGI:96443)
  Ighg2b	(MGI:96445)
  Ighg2c	(MGI:2686979)
  Ighg3	(MGI:2144790)

• Mutation details: The mouse Ighg1 locus hinge (exon2), CH2 (exon3), and CH3 (exon4) regions were replaced with human hinge (exon2), CH2(exon3), and CH3 (exon4) sequences. (J:326541)
• Inheritance: Not Specified

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ighg1 Mutation: 29 strains or lines available

References

• Original: J:326541 Cyagen Biosciences Inc., Cyagen Biosciences Website. 2022
• All: 1 reference(s)