Glp1r^{tm1(GLP1R)Cya}
Targeted Allele Detail

Summary

• Symbol: Glp1r^{tm1(GLP1R)Cya}
• Name: glucagon-like peptide 1 receptor; targeted mutation 1, Cyagen Biosciences
• MGI ID: MGI:7657252
• Synonyms: Glp1r^{tm1(hGLP1R)Cya}
• Gene: Glp1r Location: Chr17:31120841-31155484 bp, + strand Genetic Position: Chr17, 15.8 cM
• Alliance: Glp1r^{tm1(GLP1R)Cya} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:326541
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6N

Mutation description

• Allele Type: Targeted (Inserted expressed sequence, Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Glp1r^{tm1(GLP1R)Cya} expresses 1 gene
  Knock-in expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  GLP1R (2740)

  Glp1r

  (MGI:99571)

• Mutation details: Part of the exon 1 sequence and part of the intron 1 sequence in the mouse Glp1r gene was replaced with hGLP1R Exon 1~2 CDS (without signal peptide), hGLP1R Intron 2 and hGLP1R Exon 3~13 CDS-mGlp1r 3'UTR-hGH pA while retaining the gene sequence encoding the signal peptide of the mouse Glp1r protein. (J:326541)
• Inheritance: Not Specified

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Glp1r Mutation: 52 strains or lines available

References

• Original: J:326541 Cyagen Biosciences Inc., Cyagen Biosciences Website. 2022
• All: 1 reference(s)