Col7a1^{em1(COL7A1*)Cya}
Endonuclease-mediated Allele Detail

Summary

• Symbol: Col7a1^{em1(COL7A1*)Cya}
• Name: collagen, type VII, alpha 1; endonuclease-mediated mutation 1, Cyagen Biosciences
• MGI ID: MGI:7657231
• Synonyms: Col7a1^{em2(hCOL7A1*c.6527dupC)Cya}
• Gene: Col7a1 Location: Chr9:108782654-108813943 bp, + strand Genetic Position: Chr9, 59.63 cM
• Alliance: Col7a1^{em1(COL7A1*)Cya} page

Mutation origin

• Strain of Origin: C57BL/6N

Mutation description

• Allele Type: Endonuclease-mediated (Inserted expressed sequence, Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Col7a1^{em1(COL7A1*)Cya} expresses 1 gene
  Knock-in expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  COL7A1 (1294)

  Col7a1

  (MGI:88462)

• Mutation details: The c.6527dupC mutation is introduced into the exon 81 of the existing humanized COL7A1 gene in B6-hCOL7A1 mice (Catalog Number: C001428) using gene editing technology. (J:326541)
• Inheritance: Not Specified

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Col7a1 Mutation: 108 strains or lines available

References

• Original: J:326541 Cyagen Biosciences Inc., Cyagen Biosciences Website. 2022
• All: 1 reference(s)