Cftr^tm1(CFTR)Cya
Targeted Allele Detail

Summary

• Symbol: Cftr^tm1(CFTR)Cya
• Name: cystic fibrosis transmembrane conductance regulator; targeted mutation 1, Cyagen Biosciences
• MGI ID: MGI:7657226
• Synonyms: Cftr^{tm1(hCFTR)Cya}
• Gene: Cftr Location: Chr6:18170686-18322767 bp, + strand Genetic Position: Chr6, 8.1 cM, cytoband A3
• Alliance: Cftr^tm1(CFTR)Cya page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:326541
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6N

Mutation description

• Allele Type: Targeted (Inserted expressed sequence, Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Cftr^tm1(CFTR)Cya expresses 1 gene
  Knock-in expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  CFTR (1080)

  Cftr	(MGI:88388)

• Mutation details: The region from ~9.5kb upstream to ~1.2kb downstream of mouse Cftr gene was replaced with the region from ~40.1kb upstream to ~25kb downstream of human CFTR gene. (J:326541)
• Inheritance: Not Specified

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Cftr Mutation: 97 strains or lines available

References

• Original: J:326541 Cyagen Biosciences Inc., Cyagen Biosciences Website. 2022
• All: 1 reference(s)