B2m^em2Cya
Endonuclease-mediated Allele Detail

Summary

• Symbol: B2m^em2Cya
• Name: beta-2 microglobulin; endonuclease-mediated mutation 2, Cyagen Biosciences
• MGI ID: MGI:7657215
• Synonyms: B2m^em1Cya
• Gene: B2m Location: Chr2:121978168-121983563 bp, + strand Genetic Position: Chr2, 60.55 cM, cytoband F1-F3
• Alliance: B2m^em2Cya page

Mutation origin

• Strain of Origin: NOD.Cg-Prkdc^scid/Cya

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: NKG B2m KO mice are constructed by knocking out the B2m gene on the background of NKG mice. Compared with NKG mice, NKG B2m KO mice have a significantly longer survival period after PBMC transplantation and can be used for long-term studies of PBMC immune system reconstitution. (J:326541)
• Inheritance: Not Specified

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any B2m Mutation: 119 strains or lines available

References

• Original: J:326541 Cyagen Biosciences Inc., Cyagen Biosciences Website. 2022
• All: 1 reference(s)