Angptl3^{tm1(ANGPTL3)Cya}
Targeted Allele Detail

Summary

• Symbol: Angptl3^{tm1(ANGPTL3)Cya}
• Name: angiopoietin-like 3; targeted mutation 1, Cyagen Biosciences
• MGI ID: MGI:7657209
• Synonyms: Angptl3^{tm1(hANGPTL3)Cya}
• Gene: Angptl3 Location: Chr4:98919191-98926429 bp, + strand Genetic Position: Chr4, 45.6 cM
• Alliance: Angptl3^{tm1(ANGPTL3)Cya} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:326541
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Targeted (Inserted expressed sequence, Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Angptl3^{tm1(ANGPTL3)Cya} expresses 1 gene
  Knock-in expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  ANGPTL3 (27329)

  Angptl3

  (MGI:1353627)

• Mutation details: The mouse endogenous region from p.S17 to ~1kb downstream of Exon 7 was replaced with the human ANGPTL3 region from p.S17 to ~1kb downstream of Exon 7. The murine signal peptide (aa.1~16) was remained. (J:326541)
• Inheritance: Not Specified

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Angptl3 Mutation: 36 strains or lines available

References

• Original: J:326541 Cyagen Biosciences Inc., Cyagen Biosciences Website. 2022
• All: 1 reference(s)