Sox12^tm1.2Vlf
Targeted Allele Detail

Summary

• Symbol: Sox12^tm1.2Vlf
• Name: SRY (sex determining region Y)-box 12; targeted mutation 1.2, Veronique Lefebvre
• MGI ID: MGI:7647199
• Gene: Sox12 Location: Chr2:152235531-152239966 bp, - strand Genetic Position: Chr2, 74.94 cM
• Alliance: Sox12^tm1.2Vlf page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:175338
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Mutation details: A loxP site was inserted upstream of the coding region. An FRT-flanked neo cassette with a 3' loxP site was inserted downstream of the coding region. The frt-flanked neo was removed. (J:175338)

Expression

In Mice Carrying this Mutation:

1 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Sox12 Mutation: 8 strains or lines available

References

• Original: J:175338 Bhattaram P, et al., Organogenesis relies on SoxC transcription factors for the survival of neural and mesenchymal progenitors. Nat Commun. 2010;1:9
• All: 1 reference(s)