Hbb-bt^em1(IMPC)J
Endonuclease-mediated Allele Detail

Summary

• Symbol: Hbb-bt^em1(IMPC)J
• Name: hemoglobin, beta adult t chain; endonuclease-mediated mutation 1, Jackson
• MGI ID: MGI:7643239
• Gene: Hbb-bt Location: Chr7:103461731-103463130 bp, - strand Genetic Position: Chr7, Syntenic
• Alliance: Hbb-bt^em1(IMPC)J page
• IMPC: Hbb-bt gene page

Mutation origin

• Strain of Origin: C57BL/6NJ
• Project Collection: IMPC

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: This allele was generated at The Jackson Laboratory using Cas9 and guides with spacer sequences ATAAGTGGTGAGATAGTAAG and ATGACAACCATATCTACACA that targeted exon(s) ENSMUSE00000633129.4 ENSMUSE00001034245.2 ENSMUSE00001954483.1 ENSMUSE00002158665.1 ENSMUSE00002158666.1 ENSMUSE00002158668.1 ENSMUSE00002158669.1 ENSMUSE00002158674.1 ENSMUSE00002158675.1 ENSMUSE00002158676.1 ENSMUSE00002166278.1 ENSMUSE00002166280.1 ENSMUSE00002166283.1 ENSMUSE00002166291.1 ENSMUSE00002166292.1 ENSMUSE00002166293.1 ENSMUSE00002166294.1 ENSMUSE00002194032.1. This resulted in deletion(s) of 1769 bp (location: Chr7:103461494-103463262; GRCm39). This description was generated automatically. Additional molecular information including FASTA sequence support for this allele can be found here: (IMPC Gene page) and viewed in a genome context here: (IMPC Genome Browser). (J:384794)

• Inheritance: Not Specified

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available
• Carrying any Hbb-bt Mutation: 5 strains or lines available

References

• Original: J:188991 The Jackson Laboratory, Alleles produced for the KOMP project by The Jackson Laboratory. MGI Direct Data Submission. 2012
• All: 2 reference(s)