Bcl2l11^tm1.1Mtto
Targeted Allele Detail

Summary

• Symbol: Bcl2l11^tm1.1Mtto
• Name: BCL2 like 11; targeted mutation 1.1, Toshitada Takemori
• MGI ID: MGI:7621492
• Synonyms: Bim^f
• Gene: Bcl2l11 Location: Chr2:127967958-128004467 bp, + strand Genetic Position: Chr2, 62.23 cM, cytoband F3-G1
• Alliance: Bcl2l11^tm1.1Mtto page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:301356
• Parent Cell Line: Bruce 4 (ES Cell)
• Strain of Origin: B6.Cg-Thy1^a

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Mutation details: Two loxP sites were inserted into the introns flanking exon 5 of the gene. An Frt-flanked neo cassette was removed via FLP-mediated recombination. (J:301356)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Bcl2l11 Mutation: 32 strains or lines available

References

• Original: J:301356 Sugimoto-Ishige A, et al., Bim establishes the B cell repertoire from early to late in the immune response. Int Immunol. 2020 Sep 5
• All: 1 reference(s)