L3hypdh^em1(IMPC)Mbp
Endonuclease-mediated Allele Detail

Summary

• Symbol: L3hypdh^em1(IMPC)Mbp
• Name: L-3-hydroxyproline dehydratase (trans-); endonuclease-mediated mutation 1, Mouse Biology Program, UC Davis
• MGI ID: MGI:7620415
• Gene: L3hypdh Location: Chr12:72120202-72132213 bp, - strand Genetic Position: Chr12, 30.2 cM, cytoband C3
• Alliance: L3hypdh^em1(IMPC)Mbp page
• IMPC: L3hypdh gene page

Mutation origin

• Strain of Origin: C57BL/6NCrl
• Project Collection: IMPC

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: This allele was generated at University of California, Davis using Cas9 and guides with spacer sequences ATACACTATCTGTTAACTAC and TAGTATGGGCTCACTTAACA that targeted exon(s) ENSMUSE00001310718.2. This resulted in deletion(s) of 4 bp (location: Chr12:72126895-72126898; GRCm39), 793 bp (location: Chr12:72125871-72126663; GRCm39). This description was generated automatically. Additional molecular information including FASTA sequence support for this allele can be found here: (IMPC Gene page) and viewed in a genome context here: (IMPC Genome Browser). (J:384794)

• Inheritance: Not Specified

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any L3hypdh Mutation: 28 strains or lines available

References

• Original: J:265051 MGI and IMPC, MGI Load of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC). Database Release. 2018-2023
• All: 2 reference(s)