Hcfc1r1^em1(IMPC)Mbp
Endonuclease-mediated Allele Detail

Summary

• Symbol: Hcfc1r1^em1(IMPC)Mbp
• Name: host cell factor C1 regulator 1 (XPO1-dependent); endonuclease-mediated mutation 1, Mouse Biology Program, UC Davis
• MGI ID: MGI:7619079
• Gene: Hcfc1r1 Location: Chr17:23892570-23894201 bp, + strand Genetic Position: Chr17, 11.98 cM
• Alliance: Hcfc1r1^em1(IMPC)Mbp page
• IMPC: Hcfc1r1 gene page

Mutation origin

• Strain of Origin: C57BL/6NCrl
• Project Collection: IMPC

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: This allele was generated at University of California, Davis using Cas9 and guides with spacer sequences CAGGCACGTCCGGAATCGAG and GGAGCCAGTCGGCCACTGCG that targeted exon(s) ENSMUSE00000136263.4 ENSMUSE00000136264.2 ENSMUSE00000136265.5 ENSMUSE00000612379.2 ENSMUSE00000612380.5 ENSMUSE00000753925.2 ENSMUSE00000986111.2 ENSMUSE00000990521.2 ENSMUSE00001014006.2 ENSMUSE00001022658.2 ENSMUSE00001038135.2 ENSMUSE00001293643.2. This resulted in deletion(s) of 1783 bp (location: Chr17:23892581-23894363; GRCm39). This description was generated automatically. Additional molecular information including FASTA sequence support for this allele can be found here: (IMPC Gene page) and viewed in a genome context here: (IMPC Genome Browser). (J:384794)

• Inheritance: Not Specified

Expression

In Structures Affected by this Mutation:

3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Hcfc1r1 Mutation: 7 strains or lines available

References

• Original: J:265051 MGI and IMPC, MGI Load of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC). Database Release. 2018-2023
• All: 3 reference(s)