Brip1^em3Peco
Endonuclease-mediated Allele Detail

Summary

• Symbol: Brip1^em3Peco
• Name: BRCA1 interacting protein C-terminal helicase 1; endonuclease-mediated mutation 3, Paula E Cohen
• MGI ID: MGI:7616327
• Synonyms: Fancj^HA
• Gene: Brip1 Location: Chr11:85948964-86092019 bp, - strand Genetic Position: Chr11, 51.61 cM
• Alliance: Brip1^em3Peco page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Epitope tag)
• Mutation: Insertion
• CRISPR-targeting introduced 6xHis and HA tag sequences, a mutated PAM sequence, and stop codon. (J:346200)
• Inheritance: Not Specified

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Brip1 Mutation: 65 strains or lines available

References

• Original: J:346200 Horan TS, et al., The DNA helicase FANCJ (BRIP1) functions in double strand break repair processing, but not crossover formation during prophase I of meiosis in male mice. PLoS Genet. 2024 Feb;20(2):e1011175
• All: 1 reference(s)