Neurog2^tm1.1Cschu
Targeted Allele Detail

Summary

• Symbol: Neurog2^tm1.1Cschu
• Name: neurogenin 2; targeted mutation 1.1, Carol Schuurmans
• MGI ID: MGI:7612301
• Gene: Neurog2 Location: Chr3:127426784-127429280 bp, + strand Genetic Position: Chr3, 56.54 cM, cytoband H1
• Alliance: Neurog2^tm1.1Cschu page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:310880
• Parent Cell Line: G4 (ES Cell)
• Strain of Origin: (129S6/SvEvTac x C57BL/6NCrl)F1

Mutation description

• Allele Type: Targeted (Epitope tag, Reporter)
• Mutation: Insertion
• Mutation details: A targeting vector inserted a Flag-IRES-mCherry and loxP flanked neo-selection cassette at the STOP codon of the Neurog2 gene. Mice were bred to a Cre-expressing line to remove the neo cassette. (J:101977, J:310880)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Neurog2 Mutation: 18 strains or lines available

References

• Original: J:310880 Han S, et al., Proneural genes define ground-state rules to regulate neurogenic patterning and cortical folding. Neuron. 2021 Sep 15;109(18):2847-2863.e11
• All: 3 reference(s)