Ca8^em1(IMPC)Bay
Endonuclease-mediated Allele Detail

Summary

• Symbol: Ca8^em1(IMPC)Bay
• Name: carbonic anhydrase 8; endonuclease-mediated mutation 1, Baylor College of Medicine
• MGI ID: MGI:7610742
• Gene: Ca8 Location: Chr4:8143362-8239041 bp, - strand Genetic Position: Chr4, 3.53 cM
• Alliance: Ca8^em1(IMPC)Bay page
• IMPC: Ca8 gene page

Mutation origin

• Strain of Origin: C57BL/6N
• Project Collection: IMPC

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: This allele was generated at Baylor College of Medicine using Cas9 and guides with spacer sequences TCTATGTACACCCATGATAG and TGTTGTAGGGATTACTTCGG that targeted exon(s) ENSMUSE00000253681.2. This resulted in deletion(s) of 4 bp (location: Chr4:8221200-8221203; GRCm39), 1480 bp (location: Chr4:8221260-8222739; GRCm39) and insertion of 34 bp (location: chr8:8148406; GRCm39). This description was generated automatically. Additional molecular information including FASTA sequence support for this allele can be found here: (IMPC Gene page) and viewed in a genome context here: (IMPC Genome Browser). (J:384794)

• Inheritance: Not Specified

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Ca8 Mutation: 23 strains or lines available

References

• Original: J:265051 MGI and IMPC, MGI Load of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC). Database Release. 2018-2023
• All: 2 reference(s)