Rr470^em1Kigo
Endonuclease-mediated Allele Detail

Summary

• Symbol: Rr470^em1Kigo
• Name: regulatory region 470; endonuclease-mediated mutation 1, Qiong Wu
• MGI ID: MGI:7610513
• Synonyms: Meg8-DMR^KO
• Gene: Rr470 Location: unknown Genetic Position: Chr12, Syntenic
• Alliance: Rr470^em1Kigo page

Mutation origin

• Strain of Origin: (DBA/2J x C57BL/6J)F1

Mutation description

• Allele Type: Endonuclease-mediated (Modified regulatory region)
• Mutation: Intragenic deletion
• Mutation details: CRISPR-targeting deleted 434 bp within the Meg8 differentially methylated region within intron 2 of Rian. (J:344890)

Expression

In Mice Carrying this Mutation:

24 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Rr470 Mutation: 0 strains or lines available

References

• Original: J:344890 Zhang L, et al., Meg8-DMR as the Secondary Regulatory Region Regulates the Expression of MicroRNAs While It Does Not Affect Embryonic Development in Mice. Genes (Basel). 2023 Jun 14;14(6)
• All: 1 reference(s)