Atp10a^em1Vtrg
Endonuclease-mediated Allele Detail

Summary

• Symbol: Atp10a^em1Vtrg
• Name: ATPase, class V, type 10A; endonuclease-mediated mutation 1, Todd Graham
• MGI ID: MGI:7610141
• Synonyms: 10A^-, Atp10A^-
• Gene: Atp10a Location: Chr7:58305914-58479168 bp, + strand Genetic Position: Chr7, 33.88 cM
• Alliance: Atp10a^em1Vtrg page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR-targeting deleted exon 2 (Chr7:58389680-58390286, GRCm39). (J:344354)

Expression

In Structures Affected by this Mutation:

3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Atp10a Mutation: 71 strains or lines available

References

• Original: J:344354 Norris AC, et al., Deficiency of the lipid flippase ATP10A causes diet-induced dyslipidemia in female mice. Sci Rep. 2024 Jan 3;14(1):343
• All: 2 reference(s)