Fzd2^em1Smill
Endonuclease-mediated Allele Detail

Summary

• Symbol: Fzd2^em1Smill
• Name: frizzled class receptor 2; endonuclease-mediated mutation 1, Sarah Millar
• MGI ID: MGI:7607208
• Synonyms: Fzd2^INS
• Gene: Fzd2 Location: Chr11:102495257-102498884 bp, + strand Genetic Position: Chr11, 66.45 cM
• Alliance: Fzd2^em1Smill page

Mutation origin

• Strain of Origin: (C57BL/6J x DBA/2J)F1

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Insertion
• CRISPR-targeting inserted a single base pair resulting in a frameshift. (J:335089)
• Inheritance: Not Specified

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Fzd2 Mutation: 32 strains or lines available

References

• Original: J:335089 Zhu X, et al., FZD2 regulates limb development by mediating beta-catenin-dependent and -independent Wnt signaling pathways. Dis Model Mech. 2023 Mar 1;16(3)
• All: 1 reference(s)