Cxxc5^em1Mmda
Endonuclease-mediated Allele Detail

Summary

• Symbol: Cxxc5^em1Mmda
• Name: CXXC finger 5; endonuclease-mediated mutation 1, Meelad M Dawlaty
• MGI ID: MGI:7606854
• Synonyms: Rinf^-
• Gene: Cxxc5 Location: Chr18:35962450-35994741 bp, + strand Genetic Position: Chr18, 19.26 cM, cytoband B3
• Alliance: Cxxc5^em1Mmda page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:344836
• Parent Cell Line: v6.5 (ES Cell)
• Strain of Origin: (C57BL/6 x 129S4/SvJae)F1

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR/Cas9 technology deleted exon 2. (J:288395)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Cxxc5 Mutation: 50 strains or lines available

References

• Original: J:288395 Ravichandran M, et al., Rinf Regulates Pluripotency Network Genes and Tet Enzymes in Embryonic Stem Cells. Cell Rep. 2019 Aug 20;28(8):1993-2003.e5
• All: 2 reference(s)