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Targeted Allele Detail
Symbol: Sptbn5tm1.1Dsna
Name: spectrin beta, non-erythrocytic 5; targeted mutation 1.1, Dhasakumar S Navaratnam
MGI ID: MGI:7596140
Synonyms: Spnb5-
Gene: Sptbn5  Location: Chr2:119871974-119916159 bp, - strand  Genetic Position: Chr2, 60.11 cM
Alliance: Sptbn5tm1.1Dsna page
Germline Transmission:  Earliest citation of germline transmission: J:345361
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129S/SvEv
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
Mutation detailsA loxP-flanked neomycin selection cassette was inserted upstream of exon 2 and a third loxP site was inserted downstream of exon 2. Cre-mediated recombination removed both the selection cassette and exon 2. (J:345361)
View phenotypes and curated references for all genotypes (concatenated display).
In Structures Affected by this Mutation: 1 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Sptbn5 Mutation:  59 strains or lines available
Original:  J:345361 Stankewich MC, et al., Outer hair cell function is normal in betaV spectrin knockout mice. Hear Res. 2022 Sep 15;423:108564
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
MGI 6.13
The Jackson Laboratory