Pde6b^m1
Spontaneous Allele Detail

Summary

• Symbol: Pde6b^m1
• Name: phosphodiesterase 6B, cGMP, rod receptor, beta polypeptide; mutation 1
• MGI ID: MGI:7593958
• Gene: Pde6b Location: Chr5:108536239-108579609 bp, + strand Genetic Position: Chr5, 53.07 cM
• Alliance: Pde6b^m1 page

Mutation origin

• Strain of Origin: KM/Zzng

Mutation description

• Allele Type: Spontaneous (Null/knockout)
• Mutation: Single point mutation
• Mutation details: This spontaneous C-to-A mutation, found in the Kunming strain, changes tyrosine codon 347 (TAC) in exon 7 to a stop codon (TAA). (J:273686)
• Inheritance: Recessive

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Pde6b Mutation: 123 strains or lines available

References

• Original: J:273686 Yan W, et al., A Natural Occurring Mouse Model with Adgrv1 Mutation of Usher Syndrome 2C and Characterization of its Recombinant Inbred Strains. Cell Physiol Biochem. 2018;47(5):1883-1897
• All: 1 reference(s)