Tg(Myh6-Slc25a3)2Cpbl
Transgene Detail

Summary

• Symbol: Tg(Myh6-Slc25a3)2Cpbl
• Name: transgene insertion 2, Christopher Baines
• MGI ID: MGI:7593775
• Synonyms: Tg2
• Transgene: Tg(Myh6-Slc25a3)2Cpbl Location: unknown
• Alliance: Tg(Myh6-Slc25a3)2Cpbl page

Transgene origin

• Strain of Origin: FVB/N

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(Myh6-Slc25a3)2Cpbl expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Slc25a3 (MGI:1353498)

• Tg(Myh6-Slc25a3)2Cpbl expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Myh6 (MGI:97255)

• Mutation details: The alpha-myosin heavy chain promoter drives expression of a mouse PiC (Slc25a3) cDNA. Two transgenic lines were generated; Tg2 exhibits ~ 6 fold increased expression levels of PiC in the heart. (J:225636)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:225636 Gutierrez-Aguilar M, et al., Genetic manipulation of the cardiac mitochondrial phosphate carrier does not affect permeability transition. J Mol Cell Cardiol. 2014 Jul;72:316-25
• All: 1 reference(s)