Tg(VAV1-EGFP)1Forsb
Transgene Detail

Summary

• Symbol: Tg(VAV1-EGFP)1Forsb
• Name: transgene insertion 1, E Camilla Forsberg
• MGI ID: MGI:7593595
• Transgene: Tg(VAV1-EGFP)1Forsb Location: unknown
• Alliance: Tg(VAV1-EGFP)1Forsb page

Transgene origin

• Strain of Origin: C57BL/6

Transgene description

• Transgene Type: Transgenic (Reporter)
• Mutation: Insertion
• Mutation details: A bicistronic sequence coding for EGFP and loxP-stop-loxP-HcRed was placed downstream of human VAV1 promoter sequence and upstream of Vav1 enhancer sequence. The entire construct was flanked by two 250 bp core elements from chicken beta globulin insulator. Multiple founders were used to establish a colony, with line 1 representing the strain distributed by MMRRC (MMRRC:043614-UCD). Characterization of this line revealed no HcRed fluorescence after Cre-mediated recombination of loxP sites. (J:278594)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:278594 Perez-Cunningham J, et al., Hematopoietic stem cell-specific GFP-expressing transgenic mice generated by genetic excision of a pan-hematopoietic reporter gene. Exp Hematol. 2016 Aug;44(8):755-764.e1
• All: 1 reference(s)