Tnf^em1Cya
Endonuclease-mediated Allele Detail

Summary

• Symbol: Tnf^em1Cya
• Name: tumor necrosis factor; endonuclease-mediated mutation 1, Cyagen Biosciences
• MGI ID: MGI:7587194
• Synonyms: Tnf^em1
• Gene: Tnf Location: Chr17:35418357-35420983 bp, - strand Genetic Position: Chr17, 18.59 cM
• Alliance: Tnf^em1Cya page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Exon 1~4 will be selected as target site. (J:379193)
• Inheritance: Not Specified

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Tnf Mutation: 48 strains or lines available

References

• Original: J:379193 Yuan HJ, et al., Glucocorticoids impair oocyte competence and trigger apoptosis of ovarian cells via activating the TNF-alpha system. Reproduction. 2020 Jul;160(1):129-140
• All: 1 reference(s)