Shroom3^em2Cya
Endonuclease-mediated Allele Detail

Summary

• Symbol: Shroom3^em2Cya
• Name: shroom family member 3; endonuclease-mediated mutation 2, Cyagen Biosciences
• MGI ID: MGI:7586503
• Synonyms: Shroom3^em1flox
• Gene: Shroom3 Location: Chr5:92831294-93113177 bp, + strand Genetic Position: Chr5, 47.29 cM, cytoband E3
• Alliance: Shroom3^em2Cya page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Conditional ready, No functional change)
• Mutation: Insertion
• Exon 5 will be selected as conditional knockout region (cKO region). (J:368643)
• Inheritance: Not Specified

Expression

In Mice Carrying this Mutation:

28 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Shroom3 Mutation: 206 strains or lines available

References

• Original: J:368643 Xu LN, et al., SHROOM3 Deficiency Aggravates Adriamycin-Induced Nephropathy Accompanied by Focal Adhesion Disassembly and Stress Fiber Disorganization. Cells. 2025 Jun 13;14(12)
• All: 3 reference(s)