Slc38a2^em1Zhxy
Endonuclease-mediated Allele Detail

Summary

• Symbol: Slc38a2^em1Zhxy
• Name: solute carrier family 38, member 2; endonuclease-mediated mutation 1, Xiaoyan Zhang
• MGI ID: MGI:7581890
• Gene: Slc38a2 Location: Chr15:96585273-96597611 bp, - strand Genetic Position: Chr15, 52.6 cM
• Alliance: Slc38a2^em1Zhxy page

Mutation origin

• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR-cas9 mediated recombination created a 10 bp (5-CCA CAA TCG C-3) deletion in exon 4. (J:345023)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Slc38a2 Mutation: 40 strains or lines available

References

• Original: J:345023 Du C, et al., Neutral amino acid transporter SLC38A2 protects renal medulla from hyperosmolarity-induced ferroptosis. Elife. 2023 Feb 1;12
• All: 1 reference(s)