Thra^em1Few
Endonuclease-mediated Allele Detail

Summary

• Symbol: Thra^em1Few
• Name: thyroid hormone receptor alpha; endonuclease-mediated mutation 1, Fredric E Wondisford
• MGI ID: MGI:7580558
• Synonyms: Thra^HA
• Gene: Thra Location: Chr11:98631539-98659832 bp, + strand Genetic Position: Chr11, 62.58 cM, cytoband D-E
• Alliance: Thra^em1Few page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Epitope tag)
• Mutation: Insertion
• CRISPR-targeting introduced a double HA epitope tag after the translation initiation codon. (J:344943)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Thra Mutation: 39 strains or lines available

References

• Original: J:344943 Minakhina S, et al., A Direct Comparison of Thyroid Hormone Receptor Protein Levels in Mice Provides Unexpected Insights into Thyroid Hormone Action. Thyroid. 2020;30(8):1193-1204
• All: 1 reference(s)