Thrb^em3Few
Endonuclease-mediated Allele Detail

Summary

• Symbol: Thrb^em3Few
• Name: thyroid hormone receptor beta; endonuclease-mediated mutation 3, Fredric E Wondisford
• MGI ID: MGI:7580557
• Synonyms: Thrb2^HA
• Gene: Thrb Location: Chr14:4431611-4809435 bp, - strand Genetic Position: Chr14, 7.08 cM, cytoband A3
• Alliance: Thrb^em3Few page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Epitope tag, Modified isoform(s))
• Mutation: Insertion
• CRISPR-targeting introduced an HA epitope tag in isoform 2. (J:344943)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Thrb Mutation: 41 strains or lines available

References

• Original: J:344943 Minakhina S, et al., A Direct Comparison of Thyroid Hormone Receptor Protein Levels in Mice Provides Unexpected Insights into Thyroid Hormone Action. Thyroid. 2020;30(8):1193-1204
• All: 1 reference(s)