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Atp9aem1Bcgen
Endonuclease-mediated Allele Detail
Summary
Symbol: Atp9aem1Bcgen
Name: ATPase, class II, type 9A; endonuclease-mediated mutation 1, Biocytogen LLC
MGI ID: MGI:7580494
Gene: Atp9a  Location: Chr2:168476358-168584290 bp, - strand  Genetic Position: Chr2, 88.99 cM, cytoband H3
Alliance: Atp9aem1Bcgen page
Mutation
origin
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Endonuclease-mediated (Null/knockout)
Mutation:    Intragenic deletion
 
Mutation detailsCRISPR/Cas9 technology generated a 223-bp deletion that deleted exons 3-4 and resulted in an open reading frame shift. (J:335674)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Expression
In Structures Affected by this Mutation: 3 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Atp9a Mutation:  78 strains or lines available
References
Original:  J:335674 Meng T, et al., ATP9A deficiency causes ADHD and aberrant endosomal recycling via modulating RAB5 and RAB11 activity. Mol Psychiatry. 2023 Mar;28(3):1219-1231
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory