Prkaa1^tm1Tong
Targeted Allele Detail

Summary

• Symbol: Prkaa1^tm1Tong
• Name: protein kinase, AMP-activated, alpha 1 catalytic subunit; targeted mutation 1, Chao Tong
• MGI ID: MGI:7578935
• Synonyms: AMPKalpha1^f
• Gene: Prkaa1 Location: Chr15:5173343-5211380 bp, + strand Genetic Position: Chr15, 1.99 cM
• Alliance: Prkaa1^tm1Tong page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:344568
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6N

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• LoxP sites were inserted to flank exon 3. (J:344568)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Prkaa1 Mutation: 46 strains or lines available

References

• Original: J:344568 Xu P, et al., AMPK regulates homeostasis of invasion and viability in trophoblasts by redirecting glucose metabolism: Implications for pre-eclampsia. Cell Prolif. 2023 Feb;56(2):e13358
• All: 1 reference(s)