Filip1l^em1Slib
Endonuclease-mediated Allele Detail

Summary

• Symbol: Filip1l^em1Slib
• Name: filamin A interacting protein 1-like; endonuclease-mediated mutation 1, Steven K Libutti
• MGI ID: MGI:7578805
• Synonyms: Filip1l^fl
• Gene: Filip1l Location: Chr16:57173640-57393167 bp, + strand Genetic Position: Chr16, 34.22 cM, cytoband C1.1
• Alliance: Filip1l^em1Slib page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Conditional ready)
• Mutation: Insertion
• Mutation details: LoxP sites were inserted to flank critical exon(s) of the gene using CRISPR/Cas9 genome editing technology. Details were not specified. (J:312351)

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Filip1l Mutation: 38 strains or lines available

References

• Original: J:312351 Kwon M, et al., FILIP1L loss is a driver of aggressive mucinous colorectal adenocarcinoma and mediates cytokinesis defects through PFDN1. Cancer Res. 2021 Aug 20
• All: 2 reference(s)