Pnpla3^{em2(PNPLA3*)Gpt}
Endonuclease-mediated Allele Detail

Summary

• Symbol: Pnpla3^{em2(PNPLA3*)Gpt}
• Name: patatin-like phospholipase domain containing 3; endonuclease-mediated mutation 2, GemPharmatech
• MGI ID: MGI:7576474
• Synonyms: Pnpla3^{em1Cin(hPNPLA3 I148M)}
• Gene: Pnpla3 Location: Chr15:84052038-84071437 bp, + strand Genetic Position: Chr15, 39.78 cM, cytoband E3
• Alliance: Pnpla3^{em2(PNPLA3*)Gpt} page

Mutation origin

• Strain of Origin: C57BL/6JGpt

Mutation description

• Allele Type: Endonuclease-mediated (Humanized sequence, Inserted expressed sequence)
• Mutations: Insertion, Intragenic deletion
• Mutation details: CRISPR-targeting replaced the endogenous coding sequence with the humanized sequence containing the amino acid substitution isoleucine with methionine at position 148 (I148M). (J:293217)
• Inheritance: Not Specified

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Pnpla3 Mutation: 28 strains or lines available

References

• Original: J:293217 GemPharmatech, GemPharmatech Website. 2020
• All: 1 reference(s)