Igf2bp1^em8Gpt
Endonuclease-mediated Allele Detail

Summary

• Symbol: Igf2bp1^em8Gpt
• Name: insulin-like growth factor 2 mRNA binding protein 1; endonuclease-mediated mutation 8, GemPharmatech
• MGI ID: MGI:7576378
• Synonyms: Igf2bp1^delete, Igf2bp1^em1Cd, Igf2bp1^em8Cd3770
• Gene: Igf2bp1 Location: Chr11:95847989-95896766 bp, - strand Genetic Position: Chr11, 59.08 cM
• Alliance: Igf2bp1^em8Gpt page

Mutation origin

• Strain of Origin: C57BL/6JGpt

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR-targeting of exons 3 and 4 deleted 3770 bp. (J:293217, J:364177)
• Inheritance: Not Specified

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Igf2bp1 Mutation: 104 strains or lines available

References

• Original: J:364177 Luo J, et al., RNA-binding protein IGF2BP1 is required for spermatogenesis in an age-dependent manner. Commun Biol. 2024 Oct 21;7(1):1362
• All: 2 reference(s)