Tg(tetO-ZNF746)158Tmd
Transgene Detail

Summary

• Symbol: Tg(tetO-ZNF746)158Tmd
• Name: transgene insertion 158, Ted M Dawson
• MGI ID: MGI:7575761
• Synonyms: TetP-PARIS-Flag
• Transgene: Tg(tetO-ZNF746)158Tmd Location: unknown
• Alliance: Tg(tetO-ZNF746)158Tmd page

Transgene origin

• Strain of Origin: (C57BL/6 x C3H)F2

Transgene description

• Transgene Type: Transgenic (Epitope tag, Humanized sequence, Inserted expressed sequence)
• Inducer: doxycycline/tetracycline
• Mutation: Insertion
• Tg(tetO-ZNF746)158Tmd expresses 1 gene
  Transgene expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  ZNF746 (155061)

  Zfp746

  (MGI:1916478)

• Tg(tetO-ZNF746)158Tmd expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  Not Specified	tetO

• Mutation details: The C-terminal Flag-tagged human ZFP746 is under the control of a tetracycline-responsive regulator. Three high copy lines were generated, lines 121, 158, and 179. (J:322197)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:322197 Jo A, et al., PARIS farnesylation prevents neurodegeneration in models of Parkinson's disease. Sci Transl Med. 2021 Jul 28;13(604)
• All: 1 reference(s)