Cd28^em2(CD28)Gpt
Endonuclease-mediated Allele Detail

Summary

• Symbol: Cd28^em2(CD28)Gpt
• Name: CD28 antigen; endonuclease-mediated mutation 2, GemPharmatech
• MGI ID: MGI:7572965
• Synonyms: Cd28^{em1Cin(hCD28)}
• Gene: Cd28 Location: Chr1:60785547-60812521 bp, + strand Genetic Position: Chr1, 30.52 cM, cytoband C1-C3
• Alliance: Cd28^em2(CD28)Gpt page

Mutation origin

• Strain of Origin: C57BL/6JGpt-Pdcd1^{em6(PDCD1)Gpt}/Gpt

Mutation description

• Allele Type: Endonuclease-mediated (Humanized sequence, Inserted expressed sequence)
• Mutations: Insertion, Intragenic deletion
• Cd28^em2(CD28)Gpt expresses 1 gene
  Knock-in expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  CD28 (940)

  Cd28	(MGI:88327)

• Mutation details: CRISPR-targeting replaced the endogenous extracellular domain coding sequence with the humanized sequence. (J:293217)
• Inheritance: Not Specified

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Cd28 Mutation: 53 strains or lines available

References

• Original: J:293217 GemPharmatech, GemPharmatech Website. 2020
• All: 1 reference(s)