Gne^em1Cmin
Endonuclease-mediated Allele Detail

Summary

• Symbol: Gne^em1Cmin
• Name: glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase; endonuclease-mediated mutation 1, Chieko Mineo
• MGI ID: MGI:7572470
• Synonyms: GNE^fl
• Gene: Gne Location: Chr4:44034075-44084177 bp, - strand Genetic Position: Chr4, 23.1 cM, cytoband B1
• Alliance: Gne^em1Cmin page

Mutation origin

• Strain of Origin: Not Specified

Mutation description

• Allele Type: Endonuclease-mediated (Conditional ready, No functional change)
• Mutation: Insertion
• Exon 3 was flanked by loxP sites via CRISPR/Cas9 technology. (J:344082)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Gne Mutation: 53 strains or lines available

References

• Original: J:344082 Peng J, et al., Hepatic sialic acid synthesis modulates glucose homeostasis in both liver and skeletal muscle. Mol Metab. 2023 Sep 28;78:101812
• All: 1 reference(s)